Загрузка...

Interaction of nitroimidazole drugs with DNA in vitro: structure-activity relationships.

An electrolytic reduction system has been developed to model the cytotoxic action of a range of nitroimidazole drugs against DNA hypoxic cells or anaerobic microorganisms. THe degree of damage induced by these drugs (measured as the release of [14C]-dT from DNA) and their relative rates of reduction...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Knox, R. J., Knight, R. C., Edwards, D. I.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1981
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010832/
https://ncbi.nlm.nih.gov/pubmed/7032569
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!