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Mechanisms of selective toxicity of metronidazole and other nitroimidazole drugs.

The selectively toxic effect of nitroimidazole drugs towards anaerobic bacteria and protozoa depends on a number of factors. The killing action of such drugs as metronidazole requires the reduction of the nitro group, a process which influences the rate of entry of the drug into the susceptible cell...

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Detalhes bibliográficos
Autor principal: Edwards, D I
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1045807/
https://ncbi.nlm.nih.gov/pubmed/7000306
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