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Mechanisms of selective toxicity of metronidazole and other nitroimidazole drugs.
The selectively toxic effect of nitroimidazole drugs towards anaerobic bacteria and protozoa depends on a number of factors. The killing action of such drugs as metronidazole requires the reduction of the nitro group, a process which influences the rate of entry of the drug into the susceptible cell...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1980
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1045807/ https://ncbi.nlm.nih.gov/pubmed/7000306 |
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