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Binary transgenic mouse model for studying the trans control of globin gene switching: Evidence that GATA-1 is an in vivo repressor of human ɛ gene expression

To test whether human GATA-1 (hGATA-1) is involved in the transcriptional control of globin gene switching, we produced transgenic mice overexpressing hGATA-1, crossed them with mice carrying a human β-globin locus yeast artificial chromosome (βYAC), and analyzed globin gene expression in their prog...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Qiliang, Clegg, Christopher, Peterson, Kenneth, Shaw, Sara, Raich, Natacha, Stamatoyannopoulos, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC20107/
https://ncbi.nlm.nih.gov/pubmed/9122214
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