Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

The study of human B cell tolerance has been hampered by difficulties in identifying a sizable population of autoreactive B lymphocytes whose fate could be readily determined. Hypothesizing that B cells expressing intrinsically autoreactive antibodies encoded by the VH4-34 heavy chain gene (VH4-34 c...

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Bibliographic Details
Main Authors: Pugh-Bernard, Aimee E., Silverman, Gregg J., Cappione, Amedeo J., Villano, Michael E., Ryan, Daniel H., Insel, Richard A., Sanz, Iñaki
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC200949/
https://ncbi.nlm.nih.gov/pubmed/11581307
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