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Feedback inhibition of Ca(2+) channels by Ca(2+) depends on a short sequence of the C terminus that does not include the Ca(2+)-binding function of a motif with similarity to Ca(2+)-binding domains

α(1C)- and α(1E)-based Ca(2+) channels differ in that the former are inhibited by Ca(2+) entering through its pore, while the latter are not. It has been proposed on the basis of analysis of α(1E)/α(1C) chimeras that the molecular determinants responsible for Ca(2+) inhibition involve both a conserv...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Εκδόθηκε σε:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Zhou, Jianming, Olcese, Riccardo, Qin, Ning, Noceti, Francesca, Birnbaumer, Lutz, Stefani, Enrico
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 1997
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122189/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2301
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