Feedback inhibition of Ca(2+) channels by Ca(2+) depends on a short sequence of the C terminus that does not include the Ca(2+)-binding function of a motif with similarity to Ca(2+)-binding domains
α(1C)- and α(1E)-based Ca(2+) channels differ in that the former are inhibited by Ca(2+) entering through its pore, while the latter are not. It has been proposed on the basis of analysis of α(1E)/α(1C) chimeras that the molecular determinants responsible for Ca(2+) inhibition involve both a conserv...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2301 |
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