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Feedback inhibition of Ca(2+) channels by Ca(2+) depends on a short sequence of the C terminus that does not include the Ca(2+)-binding function of a motif with similarity to Ca(2+)-binding domains

α(1C)- and α(1E)-based Ca(2+) channels differ in that the former are inhibited by Ca(2+) entering through its pore, while the latter are not. It has been proposed on the basis of analysis of α(1E)/α(1C) chimeras that the molecular determinants responsible for Ca(2+) inhibition involve both a conserv...

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Autors principals: Zhou, Jianming, Olcese, Riccardo, Qin, Ning, Noceti, Francesca, Birnbaumer, Lutz, Stefani, Enrico
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20082/
https://ncbi.nlm.nih.gov/pubmed/9122189
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