The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

The chemokine receptors CXCR4 and CCR5 function as coreceptors for HIV-1 entry into CD4(+) cells. During the early stages of HIV infection, viral isolates tend to use CCR5 for viral entry, while later isolates tend to use CXCR4. The pattern of expression of these chemokine receptors on T cell subset...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Bleul, Conrad C., Wu, Lijun, Hoxie, James A., Springer, Timothy A., Mackay, Charles R.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1925
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