The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

The chemokine receptors CXCR4 and CCR5 function as coreceptors for HIV-1 entry into CD4(+) cells. During the early stages of HIV infection, viral isolates tend to use CCR5 for viral entry, while later isolates tend to use CXCR4. The pattern of expression of these chemokine receptors on T cell subset...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Bleul, Conrad C., Wu, Lijun, Hoxie, James A., Springer, Timothy A., Mackay, Charles R.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1997
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1925
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