Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4

The chemokine receptors CCR5 and CXCR4 are used by human immunodeficiency virus type 1 (HIV-1) in conjunction with CD4 to infect cells. In addition, some virus strains can use alternative chemokine receptors, including CCR2b and CCR3, for infection. A polymorphism in CCR2 (CCR2-V64I) is associated w...

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Main Authors: Lee, Benhur, Doranz, Benjamin J., Rana, Shalini, Yi, Yanji, Mellado, Mario, Frade, Jose M. R., Martinez-A., Carlos, O’Brien, Stephen J., Dean, Michael, Collman, Ronald G., Doms, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC109977/
https://ncbi.nlm.nih.gov/pubmed/9696841
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