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Synthesis, cytotoxicity and antiviral activities of new neolignans related to honokiol and magnolol

A series of new bisphenol derivatives bearing allylic moieties were synthesized as potential analogs of honokiol and/or magnolol. Certain compounds exhibited specific anti-proliferation activity against SVR cells and moderate anti-HIV-1 activity in primary human lymphocytes. Compound 5h was the most...

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Detalhes bibliográficos
Main Authors: Amblard, Franck, Govindarajan, Baskaran, Lefkove, Benjamin, Rapp, Kimberly L., Detorio, Mervi, Arbiser, Jack L., Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001289/
https://ncbi.nlm.nih.gov/pubmed/17587572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.06.024
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