Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice

Oxidative burst, a critical antimicrobial mechanism of neutrophils, involves the rapid generation and release of reactive oxygen intermediates (ROIs) by the NADPH oxidase complex. Genetic mutations in an NADPH oxidase subunit, gp91 (also referred to as NOX2), are associated with chronic granulomatou...

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Detaylı Bibliyografya
Asıl Yazarlar: Graham, Daniel B., Robertson, Charles M., Bautista, Jhoanne, Mascarenhas, Francesca, Diacovo, M. Julia, Montgrain, Vivianne, Lam, Siu Kit, Cremasco, Viviana, Dunne, W. Michael, Faccio, Roberta, Coopersmith, Craig M., Swat, Wojciech
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000813/
https://ncbi.nlm.nih.gov/pubmed/17932569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32729
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