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Essential role of PI3Kδ and PI3Kγ in thymocyte survival

Class 1 phosphoinositide 3-kinases (PI3Ks), consisting of PI3Kα, β, γ, and δ, are a family of intracellular signaling molecules that play important roles in cell-mediated immune responses. In thymocytes, however, their role is less clear, although PI3Kγ is postulated to partially contribute to pre-T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Swat, Wojciech, Montgrain, Vivianne, Doggett, Teresa A., Douangpanya, Jason, Puri, Kamal, Vermi, William, Diacovo, Thomas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895732/
https://ncbi.nlm.nih.gov/pubmed/16304053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3300
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