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Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Several studies in predominantly healthy subjects have investigated the pharmacokinetics of NS2330 and its major metabolite M1. However, its pharmacokinetics have not been characterized in Alzheimer's disease patients, the target population for NS2330....

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Bibliografiske detaljer
Main Authors: Lehr, Thorsten, Staab, Alexander, Tillmann, Christiane, Trommeshauser, Dirk, Raschig, Andreas, Schaefer, Hans Guenter, Kloft, Charlotte
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000606/
https://ncbi.nlm.nih.gov/pubmed/17324246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02855.x
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