Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Several studies in predominantly healthy subjects have investigated the pharmacokinetics of NS2330 and its major metabolite M1. However, its pharmacokinetics have not been characterized in Alzheimer's disease patients, the target population for NS2330....

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Detalhes bibliográficos
Main Authors: Lehr, Thorsten, Staab, Alexander, Tillmann, Christiane, Trommeshauser, Dirk, Raschig, Andreas, Schaefer, Hans Guenter, Kloft, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000606/
https://ncbi.nlm.nih.gov/pubmed/17324246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02855.x
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