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Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation

TLX is a transcription factor that is essential for neural stem cell proliferation and self-renewal. However, the molecular mechanism of TLX-mediated neural stem cell proliferation and self-renewal is largely unknown. We show here that TLX recruits histone deacetylases (HDACs) to its downstream targ...

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Bibliografske podrobnosti
Main Authors: Sun, GuoQiang, Yu, Ruth T., Evans, Ronald M., Shi, Yanhong
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000559/
https://ncbi.nlm.nih.gov/pubmed/17873065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704089104
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