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Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

During mammalian embryogenesis, precise coordination of progenitor cell proliferation and differentiation is essential for proper organ size and function. The involvement of TLX (NR2E1), an orphan nuclear receptor, has been implicated in ocular development, as Tlx(−/−) mice exhibit visual impairment...

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Detalhes bibliográficos
Main Authors: Zhang, Chun-Li, Zou, Yuhua, Yu, Ruth T., Gage, Fred H., Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472905/
https://ncbi.nlm.nih.gov/pubmed/16702404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1413606
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