Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

During mammalian embryogenesis, precise coordination of progenitor cell proliferation and differentiation is essential for proper organ size and function. The involvement of TLX (NR2E1), an orphan nuclear receptor, has been implicated in ocular development, as Tlx(−/−) mice exhibit visual impairment...

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Bibliographic Details
Main Authors: Zhang, Chun-Li, Zou, Yuhua, Yu, Ruth T., Gage, Fred H., Evans, Ronald M.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472905/
https://ncbi.nlm.nih.gov/pubmed/16702404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1413606
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