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Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
Many chronic viral infections are marked by pathogen persistence and a generalized immunosuppression. The exact mechanisms by which this occurs are still unknown. Using a mouse model of persistent lymphocytic choriomeningitis virus (LCMV) infection, we demonstrate viral targeting of fibroblastic ret...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000533/ https://ncbi.nlm.nih.gov/pubmed/17878315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702579104 |
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