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Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event

In a previous study, we showed that the inositol pyrophosphate diphosphoinositol pentakisphosphate (IP(7)) physiologically phosphorylates mammalian and yeast proteins. We now report that this phosphate transfer reflects pyrophosphorylation. Thus, proteins must be prephosphorylated by ATP to prime th...

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Detalles Bibliográficos
Main Authors: Bhandari, Rashna, Saiardi, Adolfo, Ahmadibeni, Yousef, Snowman, Adele M., Resnick, Adam C., Kristiansen, Troels Z., Molina, Henrik, Pandey, Akhilesh, Werner, J. Kent, Juluri, Krishna R., Xu, Yong, Prestwich, Glenn D., Parang, Keykavous, Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000531/
https://ncbi.nlm.nih.gov/pubmed/17873058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707338104
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