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Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

Inositol pyrophosphates, also designated inositol diphosphates, possess high-energy β-phosphates that can pyrophosphorylate proteins and regulate various cellular processes. They are formed by a family of inositol hexakisphosphate kinases (IP6Ks). We have created mice with a targeted deletion of IP6...

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Autors principals: Bhandari, Rashna, Juluri, Krishna R., Resnick, Adam C., Snyder, Solomon H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268139/
https://ncbi.nlm.nih.gov/pubmed/18268345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712227105
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