Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event

In a previous study, we showed that the inositol pyrophosphate diphosphoinositol pentakisphosphate (IP(7)) physiologically phosphorylates mammalian and yeast proteins. We now report that this phosphate transfer reflects pyrophosphorylation. Thus, proteins must be prephosphorylated by ATP to prime th...

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Hauptverfasser: Bhandari, Rashna, Saiardi, Adolfo, Ahmadibeni, Yousef, Snowman, Adele M., Resnick, Adam C., Kristiansen, Troels Z., Molina, Henrik, Pandey, Akhilesh, Werner, J. Kent, Juluri, Krishna R., Xu, Yong, Prestwich, Glenn D., Parang, Keykavous, Snyder, Solomon H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000531/
https://ncbi.nlm.nih.gov/pubmed/17873058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707338104
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