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Physical plasticity of the nucleus in stem cell differentiation

Cell differentiation in embryogenesis involves extensive changes in gene expression structural reorganization within the nucleus, including chromatin condensation and nucleoprotein immobilization. We hypothesized that nuclei in naive stem cells would therefore prove to be physically plastic and also...

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Autors principals: Pajerowski, J. David, Dahl, Kris Noel, Zhong, Franklin L., Sammak, Paul J., Discher, Dennis E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000408/
https://ncbi.nlm.nih.gov/pubmed/17893336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702576104
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