Power-Law Rheology of Isolated Nuclei with Deformation Mapping of Nuclear Substructures

Force-induced changes in genome expression as well as remodeling of nuclear architecture in development and disease motivate a deeper understanding of nuclear mechanics. Chromatin and green fluorescent protein-lamin B dynamics were visualized in a micropipette aspiration of isolated nuclei, and both...

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Main Authors: Dahl, Kris Noel, Engler, Adam J., Pajerowski, J. David, Discher, Dennis E.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2005
Teme:
Cell Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366783/
https://ncbi.nlm.nih.gov/pubmed/16055543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062554
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