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Persistence in muscle of an adenoviral vector that lacks all viral genes

Genetic correction of inherited muscle diseases, such as Duchenne muscular dystrophy, will require long term expression of the recombinant protein following gene transfer. We have shown previously that a new adenoviral vector that lacks all viral genes expressed both full-length dystrophin and β-gal...

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Autori principali: Chen, Hsiao-Huei, Mack, Lisa M., Kelly, Robert, Ontell, Marcia, Kochanek, Stefan, Clemens, Paula R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC19970/
https://ncbi.nlm.nih.gov/pubmed/9050832
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