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Cationic Liposome Conjugation to Recombinant Adenoviral Vector Reduces Viral Antigenicity

Adenoviral (Ad) vectors are commonly used in gene therapy trials because of their efficiency in gene transfer. However, their use is limited by immune responses that reduce transgene expression and decrease the efficacy of repeated vector administration. In this study, we demonstrated that conjugati...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Natsume, Atsushi, Mizuno, Masaaki, Ryuke, Yasushi, Yoshida, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926462/
https://ncbi.nlm.nih.gov/pubmed/10804282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00953.x
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