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Cationic Liposome Conjugation to Recombinant Adenoviral Vector Reduces Viral Antigenicity

Adenoviral (Ad) vectors are commonly used in gene therapy trials because of their efficiency in gene transfer. However, their use is limited by immune responses that reduce transgene expression and decrease the efficacy of repeated vector administration. In this study, we demonstrated that conjugati...

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Bibliografische gegevens
Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Natsume, Atsushi, Mizuno, Masaaki, Ryuke, Yasushi, Yoshida, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926462/
https://ncbi.nlm.nih.gov/pubmed/10804282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00953.x
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