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Cationic Liposomes Enhance the Rate of Transduction by a Recombinant Retroviral Vector In Vitro and In Vivo

Cationic liposomes enhanced the rate of transduction of target cells with retroviral vectors. The greatest effect was seen with the formulation DC-Chol/DOPE, which gave a 20-fold increase in initial transduction rate. This allowed an efficiency of transduction after brief exposure of target cells to...

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Detalhes bibliográficos
Main Authors: Porter, Colin D., Lukacs, Katalin V., Box, Gary, Takeuchi, Yasuhiro, Collins, Mary K. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110029/
https://ncbi.nlm.nih.gov/pubmed/9573249
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