Cationic Liposomes Enhance the Rate of Transduction by a Recombinant Retroviral Vector In Vitro and In Vivo

Cationic liposomes enhanced the rate of transduction of target cells with retroviral vectors. The greatest effect was seen with the formulation DC-Chol/DOPE, which gave a 20-fold increase in initial transduction rate. This allowed an efficiency of transduction after brief exposure of target cells to...

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Библиографические подробности
Главные авторы: Porter, Colin D., Lukacs, Katalin V., Box, Gary, Takeuchi, Yasuhiro, Collins, Mary K. L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 1998
Предметы:
Gene Therapy
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC110029/
https://ncbi.nlm.nih.gov/pubmed/9573249
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