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Cationic Liposomes Enhance the Rate of Transduction by a Recombinant Retroviral Vector In Vitro and In Vivo

Cationic liposomes enhanced the rate of transduction of target cells with retroviral vectors. The greatest effect was seen with the formulation DC-Chol/DOPE, which gave a 20-fold increase in initial transduction rate. This allowed an efficiency of transduction after brief exposure of target cells to...

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Udgivet i:J Virol
Principais autores: Porter, Colin D., Lukacs, Katalin V., Box, Gary, Takeuchi, Yasuhiro, Collins, Mary K. L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110029/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573249/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.4832-4840.1998
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