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The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na(+)–Ca(2)(+) exchanger function
Glycoside-induced cardiac inotropy has traditionally been attributed to direct Na(+)–K(+)-ATPase inhibition, causing increased intracellular [Na(+)] and consequent Ca(2+) gain via the Na(+)–Ca(2+) exchanger (NCX). However, recent studies suggested alternative mechanisms of glycoside-induced inotropy...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995692/ https://ncbi.nlm.nih.gov/pubmed/16825310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.111252 |
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