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A cardiac dihydropyridine receptor II–III loop peptide inhibits resting Ca(2+) sparks in ferret ventricular myocytes

1. We studied the effect of a peptide (Ac-10C) on cardiac ryanodine receptor (RyR) opening. This decapeptide (KKERKLARTA) is a fragment of the cardiac dihydropyridine receptor (DHPR) from the cytosolic loop between the second and third transmembrane domains (II–III loop). Studies were carried out in...

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Detalhes bibliográficos
Main Authors: Li, Yanxia, Bers, Donald M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278926/
https://ncbi.nlm.nih.gov/pubmed/11711557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.0017k.x
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