Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Na(v)1.8 and Na(v)1.9 null mice

Tetrodotoxin-resistant (TTX-R) sodium currents have been proposed to underlie sensory neuronal hyperexcitability in acute inflammatory models, but their role in chronic models is unknown. Since no pharmacological tools to separate TTX-R currents are available, this study employs Na(v)1.8 and Na(v)1....

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Detalhes bibliográficos
Main Authors: Hillsley, Kirk, Lin, Jia-Hui, Stanisz, Andre, Grundy, David, Aerssens, Jeroen, Peeters, Pieter J, Moechars, Diederik, Coulie, Bernard, Stead, Ronald H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995629/
https://ncbi.nlm.nih.gov/pubmed/16857712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.113597
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