Visceral and somatic pain modalities reveal Na(V)1.7‐independent visceral nociceptive pathways

KEY POINTS: Voltage‐gated sodium channels play a fundamental role in determining neuronal excitability. Specifically, voltage‐gated sodium channel subtype Na(V)1.7 is required for sensing acute and inflammatory somatic pain in mice and humans but its significance in pain originating from the viscera...

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Vydáno v:J Physiol
Hlavní autoři: Hockley, James R. F., González‐Cano, Rafael, McMurray, Sheridan, Tejada‐Giraldez, Miguel A., McGuire, Cian, Torres, Antonio, Wilbrey, Anna L., Cibert‐Goton, Vincent, Nieto, Francisco R., Pitcher, Thomas, Knowles, Charles H., Baeyens, José Manuel, Wood, John N., Winchester, Wendy J., Bulmer, David C., Cendán, Cruz Miguel, McMurray, Gordon
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Neuroscience ‐ Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390874/
https://ncbi.nlm.nih.gov/pubmed/28105664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272837
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