Multiple roles for Na(V)1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease–derived stimuli

Chronic visceral pain affects millions of individuals worldwide and remains poorly understood, with current therapeutic options constrained by gastrointestinal adverse effects. Visceral pain is strongly associated with inflammation and distension of the gut. Here we report that the voltage-gated sod...

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Bibliografiske detaljer
Udgivet i:Pain
Main Authors: Hockley, James R.F., Boundouki, George, Cibert-Goton, Vincent, McGuire, Cian, Yip, Ping K., Chan, Christopher, Tranter, Michael, Wood, John N., Nassar, Mohammed A., Blackshaw, L. Ashley, Aziz, Qasim, Michael, Gregory J., Baker, Mark D., Winchester, Wendy J., Knowles, Charles H., Bulmer, David C.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220011/
https://ncbi.nlm.nih.gov/pubmed/24972070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2014.06.015
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