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P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors

Activation of visceral nociceptors by inflammatory mediators contributes to visceral hypersensitivity and abdominal pain associated with many gastrointestinal disorders. Purine and pyrimidine nucleotides (e.g., ATP and UTP) are strongly implicated in this process following their release from epithel...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hockley, James R. F., Tranter, Michael M., McGuire, Cian, Boundouki, George, Cibert-Goton, Vincent, Thaha, Mohamed A., Blackshaw, L. Ashley, Michael, Gregory J., Baker, Mark D., Knowles, Charles H., Winchester, Wendy J., Bulmer, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764659/
https://ncbi.nlm.nih.gov/pubmed/26911685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3369-15.2016
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