P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors

Activation of visceral nociceptors by inflammatory mediators contributes to visceral hypersensitivity and abdominal pain associated with many gastrointestinal disorders. Purine and pyrimidine nucleotides (e.g., ATP and UTP) are strongly implicated in this process following their release from epithel...

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Udgivet i:J Neurosci
Main Authors: Hockley, James R. F., Tranter, Michael M., McGuire, Cian, Boundouki, George, Cibert-Goton, Vincent, Thaha, Mohamed A., Blackshaw, L. Ashley, Michael, Gregory J., Baker, Mark D., Knowles, Charles H., Winchester, Wendy J., Bulmer, David C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764659/
https://ncbi.nlm.nih.gov/pubmed/26911685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3369-15.2016
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