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Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat

Previous studies have failed to reveal an effect of the gastrointestinal peptide hormone ghrelin on colonic motility. In the present work, ghrelin was applied into the lumbo-sacral spinal cord in the region of defecation control centres, and a synthetic ghrelin receptor agonist, CP464709, which cros...

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Hlavní autoři: Shimizu, Yasutake, Chang, Ed C, Shafton, Anthony D, Ferens, Dorota M, Sanger, Gareth J, Witherington, Jason, Furness, John B
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995628/
https://ncbi.nlm.nih.gov/pubmed/16873401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.116160
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