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Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat

Previous studies have failed to reveal an effect of the gastrointestinal peptide hormone ghrelin on colonic motility. In the present work, ghrelin was applied into the lumbo-sacral spinal cord in the region of defecation control centres, and a synthetic ghrelin receptor agonist, CP464709, which cros...

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Bibliografische gegevens
Hoofdauteurs: Shimizu, Yasutake, Chang, Ed C, Shafton, Anthony D, Ferens, Dorota M, Sanger, Gareth J, Witherington, Jason, Furness, John B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995628/
https://ncbi.nlm.nih.gov/pubmed/16873401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.116160
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