Stimulation of dopamine D2‐like receptors in the lumbosacral defaecation centre causes propulsive colorectal contractions in rats

KEY POINTS: The pathophysiological roles of the CNS in bowel dysfunction in patients with irritable bowel syndrome and Parkinson's disease remain obscure. In the present study, we demonstrate that dopamine in the lumbosacral defaecation centre causes strong propulsive motility of the colorectum...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Naitou, Kiyotada, Nakamori, Hiroyuki, Shiina, Takahiko, Ikeda, Azusa, Nozue, Yuuta, Sano, Yuuki, Yokoyama, Takuya, Yamamoto, Yoshio, Yamada, Akihiro, Akimoto, Nozomi, Furue, Hidemasa, Shimizu, Yasutake
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Alimentary
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967751/
https://ncbi.nlm.nih.gov/pubmed/26999074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272073
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