Stimulation of dopamine D2‐like receptors in the lumbosacral defaecation centre causes propulsive colorectal contractions in rats

KEY POINTS: The pathophysiological roles of the CNS in bowel dysfunction in patients with irritable bowel syndrome and Parkinson's disease remain obscure. In the present study, we demonstrate that dopamine in the lumbosacral defaecation centre causes strong propulsive motility of the colorectum...

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Detalles Bibliográficos
Publicado en:J Physiol
Autores principales: Naitou, Kiyotada, Nakamori, Hiroyuki, Shiina, Takahiko, Ikeda, Azusa, Nozue, Yuuta, Sano, Yuuki, Yokoyama, Takuya, Yamamoto, Yoshio, Yamada, Akihiro, Akimoto, Nozomi, Furue, Hidemasa, Shimizu, Yasutake
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Alimentary
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967751/
https://ncbi.nlm.nih.gov/pubmed/26999074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272073
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