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Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat

Previous studies have failed to reveal an effect of the gastrointestinal peptide hormone ghrelin on colonic motility. In the present work, ghrelin was applied into the lumbo-sacral spinal cord in the region of defecation control centres, and a synthetic ghrelin receptor agonist, CP464709, which cros...

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Détails bibliographiques
Auteurs principaux: Shimizu, Yasutake, Chang, Ed C, Shafton, Anthony D, Ferens, Dorota M, Sanger, Gareth J, Witherington, Jason, Furness, John B
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995628/
https://ncbi.nlm.nih.gov/pubmed/16873401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.116160
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