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Sugar Binding in Lactose Permease: Anomeric State of a Disaccharide Influences Binding Structure
Lactose permease in E. coli (LacY) transports both anomeric states of disaccharides but has greater affinity for α-sugars. Molecular dynamics (MD) simulations are used to probe the protein-sugar interactions, binding structures, and global protein motions in response to sugar binding by investigatin...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995404/ https://ncbi.nlm.nih.gov/pubmed/17320103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.001 |
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