Sugar Binding in Lactose Permease: Anomeric State of a Disaccharide Influences Binding Structure

Lactose permease in E. coli (LacY) transports both anomeric states of disaccharides but has greater affinity for α-sugars. Molecular dynamics (MD) simulations are used to probe the protein-sugar interactions, binding structures, and global protein motions in response to sugar binding by investigatin...

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Hlavní autoři: Klauda, Jeffery B., Brooks, Bernard R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995404/
https://ncbi.nlm.nih.gov/pubmed/17320103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.001
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