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Development of highly sensitive fluorescent assays for fatty acid amide hydrolase

Fatty acid amide hydrolase (FAAH) is a pharmaceutical target whose inhibition may lead to valuable therapeutics. Sensitive substrates for high-throughput assays are crucial for the rapid-screening FAAH inhibitors. Here we describe the development of novel and highly sensitive fluorescent assays for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Huazhang, Nishi, Kosuke, Tsai, Hsing-Ju, Hammock, Bruce D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995106/
https://ncbi.nlm.nih.gov/pubmed/17291440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.10.041
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