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Maximizing CD8(+) T cell Responses Elicited by Peptide Vaccines Containing CpG Oligodeoxynucleotides

We assessed the ability of several factors to increase the size of tumor-antigen-specific CD8(+) T cell responses elicited by vaccines incorporating peptides and CpG-containing oligodeoxynucleotides (CpG). Neither granulocyte-macrophage colony-stimulating factor (GM-CSF) nor an immunogenic MHC class...

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Autors principals: Kochenderfer, James N., Chien, Christopher D., Simpson, Jessica L., Gress, Ronald E.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995015/
https://ncbi.nlm.nih.gov/pubmed/17584532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.04.003
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