טוען...
Mechanism of Carbamate Inactivation of FAAH: Implications for the Design of Covalent Inhibitors and In Vivo Functional Probes for Enzymes
Fatty acid amide hydrolase (FAAH) regulates a large class of signaling lipids, including the endocannabinoid anandamide. Carbamate inhibitors of FAAH display analgesic and anxiolytic properties in rodents. However, the mechanism by which carbamates inhibit FAAH remains obscure. Here, we provide bioc...
שמור ב:
Main Authors: | , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2005
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994809/ https://ncbi.nlm.nih.gov/pubmed/16298297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2005.08.011 |
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