Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis

Tumors produce multiple growth factors, but little is known about the interplay between various angiogenic factors in promoting tumor angiogenesis, growth, and metastasis. Here we show that 2 angiogenic factors frequently upregulated in tumors, PDGF-BB and FGF2, synergistically promote tumor angioge...

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Библиографические подробности
Главные авторы: Nissen, Lars Johan, Cao, Renhai, Hedlund, Eva-Maria, Wang, Zongwei, Zhao, Xing, Wetterskog, Daniel, Funa, Keiko, Bråkenhielm, Ebba, Cao, Yihai
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2007
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994630/
https://ncbi.nlm.nih.gov/pubmed/17909625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32479
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