Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis

Tumors produce multiple growth factors, but little is known about the interplay between various angiogenic factors in promoting tumor angiogenesis, growth, and metastasis. Here we show that 2 angiogenic factors frequently upregulated in tumors, PDGF-BB and FGF2, synergistically promote tumor angioge...

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Bibliografiske detaljer
Main Authors: Nissen, Lars Johan, Cao, Renhai, Hedlund, Eva-Maria, Wang, Zongwei, Zhao, Xing, Wetterskog, Daniel, Funa, Keiko, Bråkenhielm, Ebba, Cao, Yihai
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994630/
https://ncbi.nlm.nih.gov/pubmed/17909625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32479
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