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Critical role of c‐jun (NH2) terminal kinase in paracetamol‐ induced acute liver failure

BACKGROUND: Acute hepatic failure secondary to paracetamol poisoning is associated with high mortality. C‐jun (NH2) terminal kinase (JNK) is a member of the mitogen‐activated protein kinase family and is a key intracellular signalling molecule involved in controlling the fate of cells. AIM: To exami...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Henderson, Neil C, Pollock, Katharine J, Frew, John, Mackinnon, Alison C, Flavell, Richard A, Davis, Roger J, Sethi, Tariq, Simpson, Kenneth J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994347/
https://ncbi.nlm.nih.gov/pubmed/17185352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.104372
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