Critical role of c‐jun (NH2) terminal kinase in paracetamol‐ induced acute liver failure

BACKGROUND: Acute hepatic failure secondary to paracetamol poisoning is associated with high mortality. C‐jun (NH2) terminal kinase (JNK) is a member of the mitogen‐activated protein kinase family and is a key intracellular signalling molecule involved in controlling the fate of cells. AIM: To exami...

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Detalhes bibliográficos
Main Authors: Henderson, Neil C, Pollock, Katharine J, Frew, John, Mackinnon, Alison C, Flavell, Richard A, Davis, Roger J, Sethi, Tariq, Simpson, Kenneth J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Liver Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994347/
https://ncbi.nlm.nih.gov/pubmed/17185352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.104372
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