Toll‐like receptor and antiphospholipid mediated thrombosis: in vivo studies

OBJECTIVE: A study was undertaken to investigate the in vivo pathogenic role of Toll‐like receptor 4 (TLR‐4) in the antiphospholipid syndrome (APS) by studying the thrombogenic antiphospholipid (aPL) activity in lipopolysaccharide (LPS) non‐responsive (LPS–/–) mice and the association between tlr4 g...

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Autori principali: Pierangeli, Silvia S, Vega‐Ostertag, Mariano E, Raschi, Elena, Liu, Xiaowei, Romay‐Penabad, Zurina, De Micheli, Valeria, Galli, Monica, Moia, Marco, Tincani, Angela, Borghi, Maria Orietta, Nguyen‐Oghalai, Tracy, Meroni, Pier Luigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2007
Soggetti:
Extended Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994302/
https://ncbi.nlm.nih.gov/pubmed/17261530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.065037
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